• Decentralized manufacturing of anti-CD19 CAR-T cells for treatment of relapsed and refractory B cell leukemia/ lymphomas.
• Evaluation of bone marrow micro-environment mediated drug resistance in acutemyeloid leukemia.
• Identification of potential biomarker for diagnosis of acute promyelocytic leukemia

• Hamenth Kumar Palani, Saravanan Ganesan, Nithya Balasundaram, Arvind Venkatraman, Anu Korula, Aby Abraham, Biju George, Vikram Mathews “Ablation of Wnt signaling in bone marrow stromal cells overcomes microenvironment‑mediated drug resistance in acute myeloid leukemia” Scientific Reports 2024; 4:8404.
• Hamenth Kumar Palani, Saravanan Ganesan, Nithya Balasundaram, Arvind Venkatraman, Uday Kulkarni, Anu Korula, Sukesh C Nair, Thenmozhi Mani, Poonkuzhali Balasubramanian, Aby Abraham, Vinuth N Puttamallesh, Harsha Gowda, Vikram Mathews “Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia” Annals of Hematology 2024.
• Hamenth Kumar Palani, Arun Kumar Arunachalam, Mohammed Yasar, Arvind Venkatraman, Uday Kulkarni, Sharon Anbumalar Lionel, Sushil Selvarajan, Anu Korula, Aby Abraham, Biju George, Jennifer E. Adair, Rimas Orentas, Boro Dropulic, Vikram Mathews “Decentralized manufacturing of anti CD19 CAR-T cells using CliniMACS Prodigy®: real-world experience and cost analysis in India” Bone Marrow Transplantation 2022.
• Nithya Balasundaram, Saravanan Ganesan, Ezhilarasi Chendamarai, Hamenth Kumar Palani, Arvind Venkatraman, Ansu Abu Alex, Sachin David, Swathy Palani Kumar, Nair Reeshma Radhakrishnan, Mohammed Yasar, Sanjeev Krishna, Anu Korula, Uday Kulkarni, Nancy Beryl Janet, Poonkuzhali Balasubramanian, Vikram Mathews “Metabolic adaptation drives arsenic trioxide resistance in acute promyelocytic leukemia” Blood Advances 2022; 6 (2): 652–663.
• A. Fouzia, Vibhor Sharma, Saravanan Ganesan, Hamenth K Palani, Nithya Balasundaram, Sachin David, Uday P. Kulkarni, Anu Korula, Anup J. Devasia, Sukesh C. Nair, Nancy Beryl Janet, Aby Abraham, Thenmozhi Mani, Jeyaseela Lakshmanan, Poonkuzhali Balasubramanian, Biju George and Vikram Mathews “Management of relapse in acute promyelocytic leukaemia treated with up-front arsenic trioxide-based regimens” British Journal of Haematology 2021; 192, 292–299.
• Uday Kulkarni, Saravanan Ganesan, Ansu Abu Alex, Hamenth K Palani, Sachin David, Nithya Balasundaram, Arvind Venkatraman, Mani Thenmozhi, Lakshmanan Jeyaseelan, Anu Korula, Anup Devasia, Aby Abraham, Nancy Beryl Janet, Poonkuzhali Balasubramanian, Biju George, Vikram Mathews “A phase II study evaluating the role of bortezomib in the management of relapsed acute promyelocytic leukemia treated upfront with arsenic trioxide”. Cancer Medicine 2020; 9:2603–2610.
• Saravanan Ganesan*, Hamenth Kumar Palani*, Nithya Balasundaram, Sachin David, Anup J Devasia, Biju George, Vikram Mathews. “Fate of Ikaros on combining lenalidomide and proteasome inhibitor in myeloma: Potential therapeutic implication” Molecular Cancer Research 2020; 18:529–36. * Co-first author.
• Saravanan Ganesan*, Hamenth Kumar Palani*, Vairavan Lakshmanan, Nithya Balasundaram, Ansu Abu Alex, Sachin David, Arvind Venkatraman, Anu Korula, Biju George, Poonkuzhali Balasubramanian, Dasaradhi Palakodeti, Neha Vyas, Vikram Mathews “Stromal-cells down-regulate miR-23a-5p to activate protective autophagy in acute myeloid leukemia” Cell Death and Disease 2019 10:736 *Co-first author.
• Saravanan Ganesan, Ansu Abu Alex, Ezhilarasi Chendamarai, Nithya Balasundaram, Hamenth Kumar Palani, Sachin David, Udhay Kulkarni, Mohammed Aiyaz, Raja Mugasimangalam, Anu Korula , Aby Abraham, Alok Srivastava, Rose Ann Padua, Christine Chomienne, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews  “Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemia” Leukemia 2016 30(11):2169-2178.
• Ansu Abu Alex, Saravanan Ganesan, Hamenth Kumar Palani, Nithya Balasundaram, Sachin David, Kavitha M Lakshmi, Uday Prakash Kulkarni, Nisham PN, Anu Korula, Anup J Devasia, Nancy Beryl Janet, Aby Abraham, Alok Srivastava, Biju George, Rose Ann Padua, Christine Chomienne, Poonkuzhali Balasubramanian, Vikram Mathews “Arsenic trioxide enhances the NK cell cytotoxicity against acute promyelocytic leukemia while simultaneously inhibiting its bio-genesis” Frontiers in Immunology. 2018 Volume 9 Article 1357.
• Sachin David, Sukesh C Nair, G. Surender Singh, Ansu Abu Alex, Saravanan Ganesan, Hamenth Kumar Palani, Nithya Balasundaram, Kavitha M. Lakshmi, Aditi Joshi, S. Kannan, Anu Korula, Fouzia Nambiatheyil Aboobacker, Aby Abraham, Biju George, Shashikant Janardan Apte, Alok Srivastava, Vikram Mathews “Prevalence of FVIII inhibitors in severe haemophilia A patients: Effect of treatment and genetic factors in an Indian population” Haemophilia 2019; 25:67–74.
• Ramprasath T, Hamenth Kumar P, Syed Mohamed Puhari S, Senthil Murugan P, Vasudevan V, Selvam GS, “L-Arginine Ameliorates Cardiac Left Ventricular Oxidative Stress by Upregulating eNOS and Nrf2 Target Genes in Alloxan Induced Hyperglycemic Rats”.  Biochemical and Biophysical Research Communications 2012; 389–394.

Work experience

• Sep 2021 – till date – Junior Lecturer – Christian Medical College, Vellore.
• Oct 2018 – Aug 2021 – Senior Research Fellow – Christian Medical College, Vellore.
• Oct 2015 – Sep 2018 – CSIR Senior Research Fellow – Christian Medical College, Vellore.
• Aug 2012 – Sep 2015 – Junior Research Fellow – Christian Medical College, Vellore.

Awards

• Nov 2023 – Best poster presentation award (Molecular Haematology), 64 th Haematocon -– Odisha, India.
• Oct 2023 – Best poster presentation award (Medical Specialties), 13 th Annual Research Day – Christian Medical College, Vellore, India
• Dec 2019 – Abstract Achievement Award, 61 st American Society of Haematology Annual Meeting & Exposition, Florida, USA.
• Dec 2019 – Best poster presentation award, 1 st International Symposium on Bone Marrow Failure Disorders, Christian Medical College, Vellore, India.
• Aug 2019 – Best poster presentation award (Medical Specialties), 10 th Annual Research Day – Christian Medical College, Vellore, India
• Dec 2017 – Abstract Achievement Award, 59 th American Society of Haematology Annual Meeting & Exposition, Atlanta, USA.
• Oct 2015 – CSIR Senior Research Fellowship
• Aug 2016 – Tamil Nadu State Eligibility Test.

Travel Awards

• Apr 2022 – International travel grant, CSIR, India
• Apr 2022 – International travel support, ASTCT, USA.
• Dec 2019 – International travel grant, DST, India
• Apr 2017 – International travel grant, DBT, India.