• Institutional – Major Fluid research grant (PI): Generation of donor-derived, virus-specific T cells for the treatment of post-transplant viral infections. [Journal of Immunological Methods (2022).
• ICMR grant (co-investigator): CAR-T cell therapy for the treatment of relapsed/refractory B cell malignancies. [Bone Marrow Transplant (2022).
• Wellcome Trust – DBT India Alliance grant (co-investigator): Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Refractory Acute Myeloid Leukemia. [Cell transplantation, (2023)]
• Institutional – Fluid research grant (PI): Antiviral T cells enriched from the transplant donor for the management of post-transplant CMV infections in the recipient.
• Institutional – Fluid research grant (co-investigator): Cellular therapy with CD45RA depletion for the prophylaxis of CMV infections in Haploidentical stem cell transplantation.
• CDSA Research training fellowship GRANT 2019: Observership in Cincinnati Children’s Hospital and Medical College of Wisconsin in the field of “Adoptive cell therapy for viral infections” and “in-house CAR-T manufacture with CliniMACS Prodigy”.
• Institutional – Fluid research grant (co-PI): Flow cytometric characterization of phenotypic changes in T cells after PD-1 inhibition with low dose Nivolumab in Hodgkin lymphoma and correlation with clinical outcome.

• Maddali M, Arunachalam AK, Kapadia AKB, Kulkarni UP, Balasubramanian P. A Review on the Role of Molecular Genetics in the Diagnostic Workup of BCR:: ABL1-Negative Myeloproliferative Neoplasms. Indian J Med Paediatr Oncol. 2023;
• Arunachalam AK, Selvarajan S, Mani T, Janet NB, Maddali M, Lionel SA, et al. Clinical significance of end of induction measurable residual disease monitoring in B‐cell acute lymphoblastic leukemia: A single center experience. Cytometry B Clin Cytom. 2023;
• Palani HK, Arunachalam AK, Yasar M, Venkatraman A, Kulkarni U, Lionel SA, et al. Decentralized manufacturing of anti CD19 CAR-T cells using CliniMACS Prodigy®: real-world experience and cost analysis in India. Bone Marrow Transplant. 2023;58(2):160–7.
• Arunachalam AK, Palani HK, Yasar M, Kulkarni U, Mathews V, George B. Generation of good manufacturing practice grade virus-specific T cells for the management of post-transplant CMV infections. J Immunol Methods. 2022;113375.
• Kulkarni U, Arunachalam AK, Palani HK, Nair RR, Balasundaram N, Venkatraman A, et al. Haploidentical Natural Killer Cell Therapy as an Adjunct to Stem Cell Transplantation for Treatment of Refractory Acute Myeloid Leukemia. Cell Transplant. 2023;32:09636897231198178.
• Arunachalam AK, Maddali M, Janet NB, Aboobacker FN, Edison ES. Immunophenotype, Karyotype and Molecular Findings in a Case of ICF Syndrome. Indian J Hematol Blood Transfus. 2022;1–3.
• Balakrishnan B, Illangeswaran RSS, Rajamani BM, Arunachalam AK, Pai AA, Mohanan E, et al. Metformin pretreatment ameliorates busulfan-induced liver endothelial toxicity during haematopoietic stem cell transplantation. Plos One. 2023;18(10):e0293311.
• Pai AA, Mohan A, Benjamin ESB, Illangeswaran RSS, Raj IX, Janet NB, et al. NUDT15 c. 415C> T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmacogenomics Pers Med. 2021;14:1303.
• Kulkarni UP, Selvarajan S, Lionel S, Prakash MA, Palani HK, Balasundaram N, et al. Real world data with concurrent retinoic acid and arsenic trioxide for the treatment of acute promyelocytic leukemia. Blood Cancer J. 2022;12(1):1–4.
• Antonisamy N, Boddu D, John R, Korrapolu RSA, Balasubramanian P, Arunachalam AK, et al. The Outcome of Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Experience from a Referral Center in South India. Indian J Hematol Blood Transfus. 2023;1–7.
• Totadri S, Geevar T, Arunachalam AK. The Symbiotic Relationship between a Clinical Hematologist and Hematopathologist in the Management of Children with Cancer. Indian J Med Paediatr Oncol. 2023;44(05):460–3.
• Korrapolu RSA, Boddu D, John R, Antonisamy N, Geevar T, Arunachalam AK, et al. What happens to children with acute lymphoblastic leukemia in low-and middle-income countries after relapse? A single-center experience from India. Pediatr Hematol Oncol. 2023;40(5):475–84.
• Arun Kumar Arunachalam, Madhavi Maddali, Fouzia N. Aboobacker, Anu Korula, Biju George, Vikram Mathews. Eunice S Edison. Primary Immunodeficiencies in India: Molecular Diagnosis and the Role of Next-Generation Sequencing. J Clin Immunol.2021;41:393– 413.
• Arun Kumar Arunachalam, Nancy Beryl Janet, Anu Korula, Kavitha M Lakshmi, Uday P Kulkarni, Fouzia N Aboobacker, Aby Abraham, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews. Prognostic value of MRD monitoring based on BCR-ABL1 copy numbers in Philadelphia chromosome positive acute lymphoblastic leukemia. Leuk Lymphoma. 2020 Dec;61(14):3468-3475.
• Prasad D Taur, Vijaya Gowri, Ambreen Abdulwahab Pandrowala, Vaishnavi V Iyengar, Akshaya Chougule, Zainab Golwala, Shraddha Chandak, Reepa Agarwal, Purva Keni, Neha Dighe, Minnie Bodhanwala, Shakuntala Prabhu, Biju George, NA Fouzia, Eunice Sindhuvi Edison, Arun Kumar Arunachalam, Manisha Rajan Madkaikar et al. Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India. Frontiers in Immunology 12, 426. https://doi.org/10.3389/fimmu.2021.631298.
• Nancy Beryl Janet, Uday Kulkarni, Arunachalam Kumar Arun, Bexy Bensega, Anup J Devasia, Anu Korula, Aby Abraham, Biju George, Vikram Mathews, Poonkuzhali Balasubramanian. Systematic application of fluorescence in situ hybridization and immunophenotype profile for the identification of ZNF384 gene rearrangements in B cell acute lymphoblastic leukemia. Int J Lab Hematol. 2021;43(4):658-663.
• Aswin Anand Pai, Ajith Mohan, Esther Sathya Bama Benjamin, Raveen Stephen Stallon Illangeswaran, Infencia Xavier Raj, Nancy Beryl Janet, Arun Kumar Arunachalam, ML Kavitha, Uday Kulkarni, Anup J Devasia, NA Fouzia, Aby Abraham, Alok Srivastava, Biju George, Vikram Mathews, Anu Korula, Poonkuzhali Balasubramanian. NUDT15 c.415C>T Polymorphism Predicts 6- MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmgenomics Pers Med. 2021;14:1303-1313.
• Maddali M, Kulkarni UP, Ravindra N, Arunachalam AK, Venkatraman A, Lionel S, Manipadam MT, Devasia AJ, Korula A, Fouzia NA, Abraham A, Srivastava A, George B, Balasubramanian P, Mathews V. Mutation profile in BCR-ABL1-negative myeloproliferative neoplasms: A single-center experience from India. Hematol Oncol Stem Cell Ther. 2021 Mar 19:S1658-3876(21)00031-5. doi: 10.1016/j.hemonc.2021.03.002.
• Madhavi Maddali, Uday Prakash Kulkarni, Niveditha Ravindra, Ekta Jajodia, Arun Kumar Arunachalam, Hemamalini Suresh, et al. JAK2 exon 12 mutations in cases with JAK2V617F-negative polycythemia vera and primary myelofibrosis. Ann Hematol (2020). https://doi.org/10.1007/s00277-020-04004-7.​
• Arun Kumar Arunachalam, Hemamalini S, Eunice S. Edison, Anu Korula, Fouzia N.A, Biju George, Shaji RV, Vikram Mathews, Poonkuzhali Balasubramanian. Screening of genetic variants in ELANE mutation negative congenital neutropenia by next generation sequencing. J Clin Pathol 2019;0:1–6. doi:10.1136/jclinpath-2019-206306
• Arun Kumar Arunachalam, Sumithra S, Madhavi Maddali, Fouzia NA, Aby Abraham, Biju George, Eunice S Edison. Molecular characterization of G6PD deficiency: report of three novel G6PD variants. Indian J Hematol Blood Transfus.2019: https://doi.org/10.1007/s12288-019-01205-7
• Arun Kumar A, Senthamizhselvi A, Hemamalini S, Eunice S. Edison, Anu Korula, Fouzia N.A, Biju George, Vikram Mathews, Poonkuzhali Balasubramanian. Spectrum of ELANE mutations in congenital neutropenia – a single centre study in patients of Indian origin. J Clin Pathol. 2018 Dec;71(12):1046-1050.
• Arun Kumar Arunachalam, Hemamalini Suresh, Vikram Mathews, Poonkuzhali Balasubramanian. Allele specific PCR: a cost effective screening method for MPL mutations in myeloproliferative neoplasms. Indian J Hematol Blood Transfus. 2018 Oct;34(4):765-767
• Arun AK, Senthamizhselvi A, Mani S, Vinodhini K, Janet NB, Lakshmi KM, Abraham A, George B, Srivastava A, Srivastava VM, Mathews V, Balasubramanian P. Frequency of rare BCR-ABL1 fusion transcripts in chronic myeloid leukemia patients. Int J Lab Hematol. 2017 Jun; 39(3): 235-242. doi: 10.1111/ijlh.12616. PubMed PMID: 28035733.
• Arun Kumar Arunachalam, Mili Jain, Ashutosh Kumar, Rashmi Kushwaha, Uma Shankar Singh and Anil Kumar Tripathi. Megakaryocytes in Chronic Phase of Chronic Myeloid Leukemia: A Descriptive Case Series. Annals of Pathology And Laboratory Medicine. 2016;3(3):A176-182.
• Preeti A, Arunachalam AK, Pradeep Y, Mati GM. Bilateral synchronous high-grade serous carcinoma and clear cell carcinoma in right and left ovaries with immunohistochemical confirmation: an exceptional finding. Indian J Pathol Microbiol. 2014 Oct-Dec;57(4):623-5. doi: 10.4103/0377-4929.142706.​

Educational Qualification:

Work experience:

• Internship – March 2010 to March 2011.
• Senior Resident: Department of Haematology, CMC Vellore. From July 2017 to July 2018.
• Assistant Professor : Department of Haematology, CMC Vellore. From July 2018 till date.