Faculty

• Generation of donor derived, virus specific cytotoxic T cells for treatment of post-transplant viral infections
• DNMT3A mutations in Acute Myeloid Leukemia.
• Study of changes in Megakaryocyte and platelet parameters and correlating with marrow fibrosis in Myeloproliferative Neoplasms and Myelodysplastic Syndromes.

• Arun Kumar Arunachalam, Madhavi Maddali, Fouzia N. Aboobacker, Anu Korula, Biju George, Vikram Mathews. Eunice S Edison. Primary Immunodeficiencies in India: Molecular Diagnosis and the Role of Next-Generation Sequencing. J Clin Immunol.2021;41:393– 413.
• Arun Kumar Arunachalam, Nancy Beryl Janet, Anu Korula, Kavitha M Lakshmi, Uday P Kulkarni, Fouzia N Aboobacker, Aby Abraham, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews. Prognostic value of MRD monitoring based on BCR-ABL1 copy numbers in Philadelphia chromosome positive acute lymphoblastic leukemia. Leuk Lymphoma. 2020 Dec;61(14):3468-3475.
• Prasad D Taur, Vijaya Gowri, Ambreen Abdulwahab Pandrowala, Vaishnavi V Iyengar, Akshaya Chougule, Zainab Golwala, Shraddha Chandak, Reepa Agarwal, Purva Keni, Neha Dighe, Minnie Bodhanwala, Shakuntala Prabhu, Biju George, NA Fouzia, Eunice Sindhuvi Edison, Arun Kumar Arunachalam, Manisha Rajan Madkaikar et al. Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India. Frontiers in Immunology 12, 426. https://doi.org/10.3389/fimmu.2021.631298.
• Nancy Beryl Janet, Uday Kulkarni, Arunachalam Kumar Arun, Bexy Bensega, Anup J Devasia, Anu Korula, Aby Abraham, Biju George, Vikram Mathews, Poonkuzhali Balasubramanian. Systematic application of fluorescence in situ hybridization and immunophenotype profile for the identification of ZNF384 gene rearrangements in B cell acute lymphoblastic leukemia. Int J Lab Hematol. 2021;43(4):658-663.
• Aswin Anand Pai, Ajith Mohan, Esther Sathya Bama Benjamin, Raveen Stephen Stallon Illangeswaran, Infencia Xavier Raj, Nancy Beryl Janet, Arun Kumar Arunachalam, ML Kavitha, Uday Kulkarni, Anup J Devasia, NA Fouzia, Aby Abraham, Alok Srivastava, Biju George, Vikram Mathews, Anu Korula, Poonkuzhali Balasubramanian. NUDT15 c.415C>T Polymorphism Predicts 6- MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy. Pharmgenomics Pers Med. 2021;14:1303-1313.
• Maddali M, Kulkarni UP, Ravindra N, Arunachalam AK, Venkatraman A, Lionel S, Manipadam MT, Devasia AJ, Korula A, Fouzia NA, Abraham A, Srivastava A, George B, Balasubramanian P, Mathews V. Mutation profile in BCR-ABL1-negative myeloproliferative neoplasms: A single-center experience from India. Hematol Oncol Stem Cell Ther. 2021 Mar 19:S1658-3876(21)00031-5. doi: 10.1016/j.hemonc.2021.03.002.
• Madhavi Maddali, Uday Prakash Kulkarni, Niveditha Ravindra, Ekta Jajodia, Arun Kumar Arunachalam, Hemamalini Suresh, et al. JAK2 exon 12 mutations in cases with JAK2V617F-negative polycythemia vera and primary myelofibrosis. Ann Hematol (2020). https://doi.org/10.1007/s00277-020-04004-7.​
• Arun Kumar Arunachalam, Hemamalini S, Eunice S. Edison, Anu Korula, Fouzia N.A, Biju George, Shaji RV, Vikram Mathews, Poonkuzhali Balasubramanian. Screening of genetic variants in ELANE mutation negative congenital neutropenia by next generation sequencing. J Clin Pathol 2019;0:1–6. doi:10.1136/jclinpath-2019-206306
• Arun Kumar Arunachalam, Sumithra S, Madhavi Maddali, Fouzia NA, Aby Abraham, Biju George, Eunice S Edison. Molecular characterization of G6PD deficiency: report of three novel G6PD variants. Indian J Hematol Blood Transfus.2019: https://doi.org/10.1007/s12288-019-01205-7
• Arun Kumar A, Senthamizhselvi A, Hemamalini S, Eunice S. Edison, Anu Korula, Fouzia N.A, Biju George, Vikram Mathews, Poonkuzhali Balasubramanian. Spectrum of ELANE mutations in congenital neutropenia - a single centre study in patients of Indian origin. J Clin Pathol. 2018 Dec;71(12):1046-1050.
• Arun Kumar Arunachalam, Hemamalini Suresh, Vikram Mathews, Poonkuzhali Balasubramanian. Allele specific PCR: a cost effective screening method for MPL mutations in myeloproliferative neoplasms. Indian J Hematol Blood Transfus. 2018 Oct;34(4):765-767
• Arun AK, Senthamizhselvi A, Mani S, Vinodhini K, Janet NB, Lakshmi KM, Abraham A, George B, Srivastava A, Srivastava VM, Mathews V, Balasubramanian P. Frequency of rare BCR-ABL1 fusion transcripts in chronic myeloid leukemia patients. Int J Lab Hematol. 2017 Jun; 39(3): 235-242. doi: 10.1111/ijlh.12616. PubMed PMID: 28035733.
• Arun Kumar Arunachalam, Mili Jain, Ashutosh Kumar, Rashmi Kushwaha, Uma Shankar Singh and Anil Kumar Tripathi. Megakaryocytes in Chronic Phase of Chronic Myeloid Leukemia: A Descriptive Case Series. Annals of Pathology And Laboratory Medicine. 2016;3(3):A176-182.
• Preeti A, Arunachalam AK, Pradeep Y, Mati GM. Bilateral synchronous high-grade serous carcinoma and clear cell carcinoma in right and left ovaries with immunohistochemical confirmation: an exceptional finding. Indian J Pathol Microbiol. 2014 Oct-Dec;57(4):623-5. doi: 10.4103/0377-4929.142706.​

Educational Qualification:

Degree	University / College	Year
MBBS	KAP Viswanatham Govt. Medical College, Trichy, Tamil Nadu	August 2005 - February 2010
MD Pathology	King George Medical University, Lucknow, Uttar Pradesh	May 2012 - June 2015
Post PG(MD) fellowship in Molecular Haematology	Christian Medical College, Vellore	July 2015 - July 2017

Work experience:

• Internship –March 2010 to March 2011.
• Senior Resident: Department of Haematology, CMC Vellore. From July 2017 to July 2018.
• Assistant Professor : Department of Haematology, CMC Vellore. From July 2018 till date.